Hemophilia Navigator™

Bleeding Disorders

Rosenthal’s Disease

Rosenthal's Disease can also be known as Hemophilia C, Plasma Thromboplastin Antecedent (PTA) Deficiency, Rosenthal Syndrome and Factor XI deficiency.

It is inherited in an autosomal dominant fashion, which means it affects men and women equally.  Factor XI deficiency may have milder symptoms that those of hemophilia, but there can be quite a bit of variability with this deficiency.  Individuals are not likely to bleed spontaneously, and hemorrhage normally occurs after trauma or surgery.  Joint bleeds are uncommon.  Patients are more prone to bruising, nosebleeds, or blood in the urine.