Hemophilia Navigator™

Bleeding Disorders

Factor VII Deficiency

Factor VII deficiency is usually severe. In fact, patients with less than 1% Factor VII activity experience similar symptoms to hemophilia. 

People with severe factor VII are prone to joint bleeds.  In addition to spontaneous nosebleeds, people can experience bleeds in the stomach, intestines, and urinary tract.  Women can have severe menorrhagia. Diagnosis can be confirmed with a factor VII assay.  There have been instances of combined factor VII deficiencies with cases of factors II, IX and X.